Drugs: effectiveness

Rheumatoid arthritis (RA) treatment and management guidelines [7, 8] recommend starting treatment with conventional synthetic disease-modifying anti-rheumatic monotherapy (csDMARD) such as hydroxychloroquine, leflunomide, methotrexate or sulfasalazine. Today, methotrexate (MTX) is the most widely used disease-modifying antirheumatic drug (DMARD) and the first to be “chosen” [1,2] for its efficacy, safety and cost [3.6] in the therapeutic […]

Baker’s Cyst: What Are They? Who Suffers?

Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease, also referred to as systemic connectivity with elective joint localization, with an erosive, deforming character and with a chronic-progressive trend that affects approximately 1% of the world population. This condition is characterized by the infiltration of neutrophils into the soft tissues which leads to hypertrophy of […]

Effects of rheumatoid arthritis on sexual activity and relationships

Living with a disease such as rheumatoid arthritis (RA) is not at all easy, one finds oneself facing it in everyday life with fluctuating phases; days in which it seems to have “won” in the morning and days when the disease is in an acute phase, in which even the most banal “gesture” like tying […]

Why aren’t biologics used right away if they’re so effective?

Although the etiopathogenesis of rheumatoid arthritis is not yet well understood, in the 1990s it was shown that chronic inflammation is caused by a disruption of the physiological balance between pro-inflammatory (in favor of inflammation) and anti-inflammatory proteins. (which inhibit inflammation). These pro-inflammatory proteins are termed CYTOKINES. Cytokines are produced by cells of the immune […]


“Tonight I’m launching a new Precision Medicine Initiative to bring us closer to curing diseases like cancer and diabetes — and to give all of us access to the personalized information we need to keep ourselves and our families healthier” Barack Obama, 20 Gennaio 2015   Several years have passed since the former President of […]

Physical activity and Rheumatoid Arthritis: THE IMPORTANCE OF CORRECT MOVEMENT

It is widely recognized that regular exercise and physical activity provide multiple health benefits to the general population and to patients with chronic diseases. There are those who practice it for pleasure and those for work, those who appreciate its creative side and those who, while not practicing it, recognize its emotional power and the […]


Polyunsaturated fatty acids are fatty acids that have more than one C = C double bond inside the molecule, in fact they differ from saturated fats precisely for their molecular-geometric composition. They belong to the polyunsaturated fatty acids, families of fats such as: omega-3, omega-6 and omega-9, which are relevant from a nutritional point of […]


The outbreak of coronavirus left the world by surprise and unprepared. The new SARS-COVID 19 has generated a lot of concerns above the population, bringing uncertainty especially in immunosuppressed patients, patients with immune system diseases. However, their concerns are justified and understandable since Covid-19 affects lung tissue causing extensive lesions at the alveolar level. Although […]